I’ve been dealing with ongoing issues related to two topical products I’ve sold successfully on Amazon for over a year. Both are legally sold in the U.S. under the FDA OTC monograph system and are properly labeled as external-use only. Each contains a well-known active ingredient that is compliant under CFR guidelines and falls within the FDA’s approved OTC concentration range.

Despite this, both ASINs were recently removed and flagged as “unapproved drugs” or “consumable products” that don’t meet Amazon’s standards. I’ve submitted MSDS documentation, FDA monograph references, updated Drug Facts panels, and a full compliance explanation. However, the appeals continue to get denied — often with vague or copy/paste responses.

In one case, the listing was wrongly flagged due to an old image that’s no longer in use (updated months ago). In the other, it appears the system may be incorrectly classifying the product as a consumable, despite clear “external use only” labeling.

I’ve asked for a manual review by the compliance team, but I haven’t been able to get it escalated.

Has anyone had success getting a situation like this resolved when a product is flagged incorrectly due to system issues or lingering image data?

Any advice or ways to trigger a true compliance-level review would be appreciated. I’ve already submitted extensive documentation, but I’m open to suggestions from sellers who’ve been through something similar.

Any help would be superrrr helpful!